HEMGN

Across TCGA patient cohorts, HEMGN mutation is significantly associated with the RNA expression of many other genes, with 6,167 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HEMGN-associated genes across cancer lineages are RN7SL134P, MIA-RAB4B, and AATF. Each is linked with HEMGN in more than 2 cancer types. Because this analysis shows association rather than direction, both HEMGN-to-partner and partner-to-HEMGN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by HEMGN-low versus HEMGN-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEMGN→partner) and Y-score (partner→HEMGN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.076	+1.792	.004	.003	3	3
COAD	MIA-RAB4B →	+0.277	+3.140	<.001	.006	3	3
UCEC	AATF →	+0.348	+1.807	.001	<.001	3	2
LUSC	RNU6-220P →	+0.162	+4.191	.001	.009	3	2
LUSC	MIR1263 →	+0.208	+4.733	<.001	.004	3	2
LUSC	LINC01177 →	+0.064	+4.578	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,167 associations by consensus.

RN7SL134P by HEMGN expression — UCEC

Explore this box plot interactively →