HECW1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HECW1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,847 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HECW1-associated genes across cancer lineages are SLC35F3, GNG5P2, and PAK6. Each is linked with HECW1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HECW1-to-partner and partner-to-HECW1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HECW1 versus SLC35F3 in GBM, with a Pearson correlation of 0.71.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HECW1→partner) and Y-score (partner→HECW1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMSLC35F3 →+1.261+0.661<.001<.00132
GBMGNG5P2 →+0.504+0.392.003.00532
LUADPAK6 →+0.864+0.595.001.00732
GBMMIPOL1 →+0.773+0.669<.001<.00132
GBMCNTNAP2 →+1.727+0.709<.001<.00132
CCRCCFBXO34 →+0.452+0.685<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,847 associations by consensus.

HECW1 vs SLC35F3 — GBM

Per-sample scatter of HECW1 vs SLC35F3 in GBM (Pearson r = 0.71).

Explore this scatter interactively →

Exploration