HECW1-IT1

Across TCGA pan-cancer cohorts, HECW1-IT1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated HECW1-IT1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher HECW1-IT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated HECW1-IT1 expression acts as an unfavorable survival marker, although some lineages such as LGG show a favorable association.

KICH, LUSC, and ACC are the cancer types where HECW1-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.081	0.904	<.001	90	view →
LUSC	OS	Tertile	II,III,IV	0.404	0.643	.005	69	view →
ACC	OS	Tertile	All	0.145	0.705	.002	57	view →
CHOL	OS	Tertile	All	0.198	0.620	.025	54	view →
CESC	OS	Tertile	IV	0.182	0.610	.027	36	view →
COAD	OS	Tertile	IV	0.187	0.699	.009	27	view →
SARC	OS	Tertile	All	0.500	0.801	<.001	21	view →
SKCM	DFS	Tertile	III,IV	0.160	0.514	.005	18	view →
LGG	DFS	Median	All	0.887	0.768	.002	12	view →
BLCA	DFS	Tertile	III,IV	0.300	0.490	.009	12	view →
HNSC	OS	Tertile	All	0.226	0.433	.025	9	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.038	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

HECW1-IT1–KICH (DFS)

Open the KICH breakdown →