HECTD3

Across TCGA patient cohorts, HECTD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,563 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible HECTD3-associated proteins across cancer lineages are TINF2, UROD, and SNX7. Each is linked with HECTD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both HECTD3-to-partner and partner-to-HECTD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HECTD3 versus TINF2 in PDAC, with a Pearson correlation of -0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HECTD3→partner) and Y-score (partner→HECTD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	TINF2 →	-0.549	-0.537	.005	.001	3	3
OV	UROD →	+0.548	+0.879	<.001	<.001	3	3
OV	SNX7 →	+0.374	+0.665	.005	.003	3	3
UCEC	ZFP36L1_S92 →	-0.772	-0.465	.003	.006	3	3
CCRCC	CTNND1_T916 →	-0.714	-0.263	.002	.002	3	3
LUAD	CTR9_S943 →	+1.183	+0.515	<.001	.006	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,563 associations by consensus.

HECTD3 vs TINF2 — PDAC

Explore this scatter interactively →