HEBP1

Across TCGA pan-cancer cohorts, HEBP1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated HEBP1 data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher HEBP1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated HEBP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LUAD, LSCC, and HNSC are the cancer types where HEBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.558	0.899	.001	12	view →
LSCC	DFS	Tertile	III,IV	0.429	1.000	.005	9	view →
HNSC	OS	Tertile	IV	0.665	0.937	.023	8	view →
GBM	OS	Tertile	All	0.315	0.511	.028	2	view →
PDAC	DFS	Quartile	All	0.503	0.317	.038	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

HEBP1–LUAD (OS)

Open the LUAD breakdown →