HEATR6

Across TCGA patient cohorts, HEATR6 protein abundance is significantly associated with the RNA expression of many other genes, with 10,656 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HEATR6-associated genes across cancer lineages are COIL, H3-3B, and PTRH2. Each is linked with HEATR6 in more than 5 cancer types. Because this analysis shows association rather than direction, both HEATR6-to-partner and partner-to-HEATR6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HEATR6 versus COIL in OV, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR6→partner) and Y-score (partner→HEATR6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	COIL →	+0.524	+0.267	<.001	.004	3	6
OV	H3-3B →	+0.689	+0.337	<.001	.001	3	6
OV	PTRH2 →	+0.539	+0.265	<.001	<.001	3	6
HNSC	DHX40 →	+0.704	+0.300	.009	<.001	3	5
BRCA	TUBD1 →	+0.442	+0.392	<.001	<.001	3	5
BRCA	RPS6KB1 →	+0.558	+0.376	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,656 associations by consensus.

HEATR6 vs COIL — OV

Explore this scatter interactively →