HEATR5A

Across TCGA cell cohorts, HEATR5A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,536 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HEATR5A-associated GO terms across cancer lineages are Endosomal transport, Cytosolic transport, and Retrograde transport, endosome to Golgi. Each is linked with HEATR5A in more than 14 cancer types. Because this analysis shows association rather than direction, both HEATR5A-to-partner and partner-to-HEATR5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by HEATR5A-low versus HEATR5A-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR5A→partner) and Y-score (partner→HEATR5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Endosomal transport →	+0.059	+1.069	<.001	<.001	3	15
BREAST	Cytosolic transport →	+0.056	+0.968	.008	.003	2	14
SOFT_TISSUE	Retrograde transport, endosome to Golgi →	+0.078	+1.028	<.001	.001	3	11
LIVER	SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition →	+0.145	+1.412	<.001	.002	3	9
OVARY	Endosome to lysosome transport →	+0.056	+1.045	<.001	<.001	3	9
SKIN	Vacuole organization →	+0.042	+0.982	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,536 associations by consensus.

Endosomal transport by HEATR5A expression — BREAST

Explore this box plot interactively →