HEATR5A

Across TCGA cell cohorts, HEATR5A mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HEATR5A-associated genes across cancer lineages are CT47B1, RGSL1, and KRTAP6-1. Each is linked with HEATR5A in more than 1 cancer types. Because this analysis shows association rather than direction, both HEATR5A-to-partner and partner-to-HEATR5A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CT47B1 grouped by HEATR5A-low versus HEATR5A-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HEATR5A→partner) and Y-score (partner→HEATR5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	CT47B1 →	+0.035	+4.544	<.001	<.001	3	2
BLOOD_Myeloma	RGSL1 →	+0.023	+3.906	.002	.009	3	1
BLOOD_Myeloma	KRTAP6-1 →	+0.110	+4.754	<.001	<.001	3	1
URINARY_TRACT	ZAN →	+0.006	+5.087	<.001	.004	3	1
BONE	CSN2 →	+0.017	+4.169	<.001	.008	3	1
BONE	KRT82 →	+0.005	+4.169	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 101 associations by consensus.

CT47B1 by HEATR5A expression — STOMACH

Explore this box plot interactively →