HDLBP

Across TCGA patient cohorts, HDLBP RNA expression is significantly associated with the protein abundance of many other proteins, with 9,210 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDLBP-associated proteins across cancer lineages are CKAP4, FAM114A1, and GALNT2. Each is linked with HDLBP in more than 5 cancer types. Because this analysis shows association rather than direction, both HDLBP-to-partner and partner-to-HDLBP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDLBP versus CKAP4 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDLBP→partner) and Y-score (partner→HDLBP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CKAP4 →	+0.566	+0.306	<.001	<.001	3	6
GBM	FAM114A1 →	+0.339	+0.216	<.001	<.001	3	6
GBM	GALNT2 →	+0.509	+0.363	<.001	<.001	3	5
PDAC	ARMC9 →	+0.365	+0.253	<.001	<.001	3	5
CCRCC	MEF2C_S396 →	-0.353	-0.255	<.001	<.001	3	4
LSCC	COPS7B →	+0.242	+0.413	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,210 associations by consensus.

HDLBP vs CKAP4 — GBM

Explore this scatter interactively →