HDGFL3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HDGFL3 protein abundance is significantly associated with the RNA expression of many other genes, with 20,648 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDGFL3-associated genes across cancer lineages are ZEB1, JAM2, and CSDC2. Each is linked with HDGFL3 in more than 8 cancer types. Because this analysis shows association rather than direction, both HDGFL3-to-partner and partner-to-HDGFL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDGFL3 versus ZEB1 in COAD, with a Pearson correlation of 0.54.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HDGFL3→partner) and Y-score (partner→HDGFL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADZEB1 →+0.711+0.448<.001<.00139
CCRCCJAM2 →+0.908+0.547<.001<.00139
CCRCCCSDC2 →+1.527+0.533<.001<.00139
BRCANXPH3 →+1.209+0.662<.001<.00139
CCRCCDACT3 →+0.752+0.542<.001<.00139
GBMGPRASP1 →+0.780+0.385<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 20,648 associations by consensus.

HDGFL3 vs ZEB1 — COAD

Per-sample scatter of HDGFL3 vs ZEB1 in COAD (Pearson r = 0.54).

Explore this scatter interactively →

Exploration