HDGFL2

Across TCGA patient cohorts, HDGFL2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,015 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HDGFL2-associated proteins across cancer lineages are AQR, RAVER1, and CHAF1A. Each is linked with HDGFL2 in more than 5 cancer types. Because this analysis shows association rather than direction, both HDGFL2-to-partner and partner-to-HDGFL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDGFL2 versus AQR in LSCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDGFL2→partner) and Y-score (partner→HDGFL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AQR →	+0.294	+0.483	<.001	<.001	3	6
GBM	RAVER1 →	+0.294	+0.365	<.001	<.001	3	5
GBM	CHAF1A →	+0.632	+0.462	<.001	<.001	3	5
GBM	GNA11 →	+0.248	+0.353	<.001	<.001	3	5
GBM	CHAF1B →	+0.634	+0.428	<.001	<.001	3	4
GBM	AGA →	-0.408	-0.251	.009	.009	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,015 associations by consensus.

HDGFL2 vs AQR — LSCC

Explore this scatter interactively →