HDGFL1

Across TCGA patient cohorts, HDGFL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,723 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HDGFL1-associated proteins across cancer lineages are SOAT1, RPE, and SHANK3. Each is linked with HDGFL1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HDGFL1-to-partner and partner-to-HDGFL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDGFL1 versus SOAT1 in GBM, with a Pearson correlation of -0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDGFL1→partner) and Y-score (partner→HDGFL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOAT1 →	-0.307	-0.169	.002	<.001	3	3
HNSC	RPE →	+0.195	+0.465	.002	.001	3	2
GBM	SHANK3 →	+0.318	+0.095	<.001	.003	3	2
LSCC	SPP2 →	+0.415	+0.123	<.001	.004	3	2
LUAD	SQSTM1 →	-0.390	-0.031	<.001	.007	3	2
LUAD	SSR3_S105 →	-0.595	-0.041	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,723 associations by consensus.

HDGFL1 vs SOAT1 — GBM

Explore this scatter interactively →