HDGF

Across TCGA patient cohorts, HDGF RNA expression is significantly associated with the protein abundance of many other proteins, with 19,224 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HDGF-associated proteins across cancer lineages are CDK1, RIF1, and RPRD2. Each is linked with HDGF in more than 8 cancer types. Because this analysis shows association rather than direction, both HDGF-to-partner and partner-to-HDGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDGF versus CDK1 in UCEC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDGF→partner) and Y-score (partner→HDGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CDK1 →	+0.659	+0.804	<.001	<.001	3	9
LSCC	RIF1 →	+0.452	+0.635	<.001	<.001	3	8
HNSC	RPRD2 →	+0.383	+0.603	<.001	<.001	3	8
GBM	SMC4 →	+0.669	+0.388	<.001	<.001	3	8
OV	CACYBP →	+0.407	+0.469	<.001	<.001	3	8
LSCC	CDC73 →	+0.285	+0.602	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,224 associations by consensus.

HDGF vs CDK1 — UCEC

Explore this scatter interactively →