HDAC5

Across TCGA patient cohorts, HDAC5 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,014 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HDAC5-associated proteins across cancer lineages are VEZF1, SND1, and PDIA4. Each is linked with HDAC5 in more than 6 cancer types. Because this analysis shows association rather than direction, both HDAC5-to-partner and partner-to-HDAC5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC5 versus VEZF1 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC5→partner) and Y-score (partner→HDAC5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	VEZF1 →	+0.492	+0.426	<.001	<.001	3	7
BRCA	SND1 →	-0.291	-0.613	<.001	<.001	3	7
CCRCC	PDIA4 →	-0.514	-0.412	<.001	<.001	3	7
GBM	HSP90B1 →	-0.390	-0.316	<.001	.002	3	7
BRCA	ARCN1 →	-0.188	-0.501	.004	.001	3	6
CCRCC	P4HB →	-0.574	-0.532	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,014 associations by consensus.

HDAC5 vs VEZF1 — GBM

Explore this scatter interactively →