HDAC3

Across TCGA patient cohorts, HDAC3 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,932 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HDAC3-associated proteins across cancer lineages are GEMIN5, NPM1, and YTHDC2. Each is linked with HDAC3 in more than 6 cancer types. Because this analysis shows association rather than direction, both HDAC3-to-partner and partner-to-HDAC3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HDAC3 versus GEMIN5 in OV, with a Pearson correlation of 0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HDAC3→partner) and Y-score (partner→HDAC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	GEMIN5 →	+0.235	+0.438	.004	.001	2	7
UCEC	NPM1 →	+0.262	+0.598	.001	.002	3	6
OV	YTHDC2 →	+0.298	+0.528	<.001	<.001	3	5
OV	DIAPH1 →	+0.621	+0.478	.005	.001	2	6
OV	HSPA4 →	+0.350	+0.364	.003	.008	2	6
OV	KDM3B →	+0.267	+0.440	.005	.002	1	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,932 associations by consensus.

HDAC3 vs GEMIN5 — OV

Explore this scatter interactively →