HCG25

Across TCGA patient cohorts, HCG25 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,141 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HCG25-associated proteins across cancer lineages are FNBP4_T479, RCOR3, and RFX5. Each is linked with HCG25 in more than 4 cancer types. Because this analysis shows association rather than direction, both HCG25-to-partner and partner-to-HCG25 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCG25 versus FNBP4_T479 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG25→partner) and Y-score (partner→HCG25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	FNBP4_T479 →	+0.484	+0.426	<.001	<.001	3	4
LSCC	RCOR3 →	+0.486	+0.463	<.001	<.001	3	4
HNSC	RFX5 →	+0.504	+0.667	<.001	<.001	3	4
BRCA	RPRD2_S928 →	+0.734	+0.385	.002	<.001	3	4
LSCC	S100A9 →	-1.137	-0.338	<.001	<.001	3	4
HNSC	SPEN_S727 →	+0.423	+0.681	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,141 associations by consensus.

HCG25 vs FNBP4_T479 — LSCC

Explore this scatter interactively →