Across TCGA patient cohorts, HCG22 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,127 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HCG22-associated proteins across cancer lineages are VCAN, COL15A1, and LIMCH1. Each is linked with HCG22 in more than 2 cancer types. Because this analysis shows association rather than direction, both HCG22-to-partner and partner-to-HCG22 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCG22→partner) and Y-score (partner→HCG22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	VCAN →	+0.666	+0.150	.001	.006	3	3
HNSC	COL15A1 →	+0.382	+1.175	.003	.001	3	3
BRCA	LIMCH1 →	+0.526	+0.149	<.001	.002	3	3
PDAC	PDXDC1_S722 →	-0.662	-0.132	.003	.006	3	3
OV	STX7 →	+0.324	+0.140	.002	.004	3	3
GBM	PI16 →	+0.600	+0.753	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,127 associations by consensus.

Exploration

HCG22 survival (RNA) · tumor vs normal (RNA) · all HCG22 data types