HCFC1R1

Across TCGA cell cohorts, HCFC1R1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,735 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible HCFC1R1-associated GO terms across cancer lineages are Caveola assembly, Actin filament depolymerization, and Lens fiber cell morphogenesis. Each is linked with HCFC1R1 in more than 10 cancer types. Because this analysis shows association rather than direction, both HCFC1R1-to-partner and partner-to-HCFC1R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caveola assembly grouped by HCFC1R1-low versus HCFC1R1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HCFC1R1→partner) and Y-score (partner→HCFC1R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Caveola assembly →	+0.145	+1.415	.001	<.001	3	10
LIVER	Actin filament depolymerization →	+0.165	+1.244	<.001	.002	2	11
SOFT_TISSUE	Lens fiber cell morphogenesis →	+0.156	+0.995	.001	.001	3	9
LUNG_NSCLC_LUSC	Positive regulation of cell-substrate junction organization →	+0.136	+1.000	<.001	.002	3	9
SOFT_TISSUE	Regulation of glutamate uptake involved in transmission of nerve impulse →	+0.164	+0.871	<.001	<.001	3	8
STOMACH	Serotonin secretion →	-1.482	-1.188	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,735 associations by consensus.

Caveola assembly by HCFC1R1 expression — OESOPHAGUS

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