HCFC1R1

Across TCGA cell cohorts, HCFC1R1 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HCFC1R1-associated genes across cancer lineages are OR10W1 and OR10G2. Each is linked with HCFC1R1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HCFC1R1-to-partner and partner-to-HCFC1R1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10W1 grouped by HCFC1R1-low versus HCFC1R1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCFC1R1→partner) and Y-score (partner→HCFC1R1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR10W1 →	+0.022	+4.977	<.001	.007	3	1
LARGE_INTESTINE	OR10G2 →	+0.074	+4.977	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

OR10W1 by HCFC1R1 expression — LARGE_INTESTINE

Explore this box plot interactively →