HCAR3

Across TCGA patient cohorts, HCAR3 RNA expression is significantly associated with the RNA expression of many other genes, with 16,807 significant associations in total. THYM shows the largest number of these associations.

The most reproducible HCAR3-associated genes across cancer lineages are HCAR2, MEFV, and TNFAIP3. Each is linked with HCAR3 in more than 32 cancer types. Because this analysis shows association rather than direction, both HCAR3-to-partner and partner-to-HCAR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCAR3 versus HCAR2 in ESCA, with a Pearson correlation of 0.86.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HCAR3→partner) and Y-score (partner→HCAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	HCAR2 →	+2.816	+1.792	<.001	<.001	3	33
LAML	MEFV →	+1.592	+0.759	<.001	<.001	3	28
CHOL	TNFAIP3 →	+1.583	+0.345	<.001	<.001	2	28
PAAD	ZC3H12A →	+1.257	+0.537	<.001	<.001	3	27
SCLC	ADCY7 →	+1.425	+0.802	<.001	<.001	3	26
DLBC	ADGRE2 →	+1.226	+0.513	<.001	.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,807 associations by consensus.

HCAR3 vs HCAR2 — ESCA

Explore this scatter interactively →