HCAR3

Across TCGA patient cohorts, HCAR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,419 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HCAR3-associated proteins across cancer lineages are CAMP, MNDA, and MPO. Each is linked with HCAR3 in more than 8 cancer types. Because this analysis shows association rather than direction, both HCAR3-to-partner and partner-to-HCAR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HCAR3 versus CAMP in GBM, with a Pearson correlation of 0.63.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HCAR3→partner) and Y-score (partner→HCAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CAMP →	+1.673	+0.616	<.001	<.001	3	9
COAD	MNDA →	+1.058	+1.465	<.001	<.001	3	9
GBM	MPO →	+1.278	+0.666	<.001	<.001	3	9
GBM	PRTN3 →	+1.247	+0.621	<.001	<.001	3	8
GBM	RETN →	+1.219	+0.586	<.001	<.001	3	8
COAD	S100A12 →	+1.497	+1.740	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,419 associations by consensus.

HCAR3 vs CAMP — GBM

Explore this scatter interactively →