HBZ

Across TCGA cell cohorts, HBZ RNA expression is significantly associated with the go_rna of many other GO terms, with 2,233 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HBZ-associated GO terms across cancer lineages are Cellular response to type I interferon, Regulation of myoblast fusion, and Pyrimidine ribonucleoside triphosphate metabolic process. Each is linked with HBZ in more than 5 cancer types. Because this analysis shows association rather than direction, both HBZ-to-partner and partner-to-HBZ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to type I interferon grouped by HBZ-low versus HBZ-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HBZ→partner) and Y-score (partner→HBZ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Cellular response to type I interferon →	+0.060	+0.052	.001	.003	3	6
UPPER_AERODIGESTIVE_TRACT	Regulation of myoblast fusion →	+0.105	+0.016	<.001	.001	3	6
LUNG_SCLC	Pyrimidine ribonucleoside triphosphate metabolic process →	+0.091	+0.090	.001	.003	3	5
LUNG_SCLC	Pyrimidine ribonucleoside triphosphate biosynthetic process →	+0.099	+0.093	<.001	.001	3	5
UPPER_AERODIGESTIVE_TRACT	Ribonucleotide metabolic process →	+0.034	+0.016	.008	.001	3	5
LUNG_SCLC	CTP biosynthetic process →	+0.101	+0.096	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,233 associations by consensus.

Cellular response to type I interferon by HBZ expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →