HBEGF

Across TCGA patient cohorts, HBEGF protein abundance is significantly associated with the RNA expression of many other genes, with 13,778 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HBEGF-associated genes across cancer lineages are DIPK1B, MAPK7, and LGALS4. Each is linked with HBEGF in more than 1 cancer types. Because this analysis shows association rather than direction, both HBEGF-to-partner and partner-to-HBEGF results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HBEGF versus DIPK1B in LSCC, with a Pearson correlation of -0.75.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HBEGF→partner) and Y-score (partner→HBEGF) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DIPK1B →	-1.464	-0.868	.001	.002	3	2
GBM	MAPK7 →	-0.594	-0.441	.007	.009	3	2
LSCC	LGALS4 →	-0.948	-0.868	.003	.002	3	2
GBM	RPL17P15 →	-0.923	-0.586	.001	.004	3	2
GBM	CRYBB2P1 →	-0.818	-0.639	.002	.004	3	1
GBM	DEPDC5 →	-0.483	-0.615	.006	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,778 associations by consensus.

HBEGF vs DIPK1B — LSCC

Explore this scatter interactively →