HBB

Across TCGA patient cohorts, HBB RNA expression is significantly associated with the protein abundance of many other proteins, with 11,534 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HBB-associated proteins across cancer lineages are SLC4A1, HBD, and ANK1. Each is linked with HBB in more than 9 cancer types. Because this analysis shows association rather than direction, both HBB-to-partner and partner-to-HBB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HBB versus SLC4A1 in OV, with a Pearson correlation of 0.74.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HBB→partner) and Y-score (partner→HBB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SLC4A1 →	+1.133	+2.225	<.001	<.001	3	10
BRCA	HBD →	+1.283	+2.004	<.001	<.001	3	10
BRCA	ANK1 →	+1.085	+2.380	<.001	<.001	3	10
BRCA	EPB42 →	+1.123	+2.341	<.001	<.001	3	10
BRCA	PPBP →	+0.992	+1.903	<.001	<.001	3	9
CCRCC	SLC4A1_S357 →	+2.130	+2.573	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,534 associations by consensus.

HBB vs SLC4A1 — OV

Explore this scatter interactively →