Across TCGA patient cohorts, HBA1 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,193 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible HBA1-associated proteins across cancer lineages are SPTB, EPB42, and ANK1. Each is linked with HBA1 in more than 9 cancer types. Because this analysis shows association rather than direction, both HBA1-to-partner and partner-to-HBA1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HBA1→partner) and Y-score (partner→HBA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	SPTB →	+1.204	+1.255	<.001	<.001	3	10
CCRCC	EPB42 →	+1.101	+1.222	<.001	<.001	3	10
CCRCC	ANK1 →	+1.089	+1.224	<.001	<.001	3	10
CCRCC	SLC4A1 →	+1.318	+1.399	<.001	<.001	3	10
CCRCC	SPTA1 →	+1.249	+1.273	<.001	<.001	3	9
BRCA	PPBP →	+0.976	+1.149	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,193 associations by consensus.

Exploration

HBA1 survival (RNA) · tumor vs normal (RNA) · all HBA1 data types