HAX1

Across TCGA patient cohorts, HAX1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,074 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible HAX1-associated genes across cancer lineages are ABCA8, DCN, and PDE1A. Each is linked with HAX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both HAX1-to-partner and partner-to-HAX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAX1 versus ABCA8 in BRCA, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAX1→partner) and Y-score (partner→HAX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ABCA8 →	-0.952	-0.257	<.001	<.001	3	7
OV	DCN →	-1.349	-0.361	.001	.001	3	6
BRCA	PDE1A →	-0.585	-0.200	<.001	.001	3	6
BRCA	CNRIP1 →	-0.781	-0.329	<.001	<.001	3	6
BRCA	JAM2 →	-0.848	-0.368	<.001	<.001	3	6
LUAD	CD1C →	-0.872	-0.199	.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,074 associations by consensus.

HAX1 vs ABCA8 — BRCA

Explore this scatter interactively →