Across TCGA patient cohorts, HAUS3 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HAUS3-associated genes across cancer lineages are ACC1, p62 Lck ligand, and ASNS. Each is linked with HAUS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAUS3-to-partner and partner-to-HAUS3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS3→partner) and Y-score (partner→HAUS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC1 →	+0.283	+3.335	.024	.005	3	2
UCEC	p62 Lck ligand →	+0.336	+2.009	.002	.017	3	2
UCEC	ASNS →	+0.405	+1.678	.001	.021	3	2
UCEC	eIF4E →	+0.150	+2.070	.040	.001	3	1
UCEC	Acetyl-a-Tubulin-Lys40 →	+0.566	+1.495	.001	.034	3	1
UCEC	MEK1 →	+0.332	+2.000	.008	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

HAUS3 survival (RNA) · tumor vs normal (RNA) · all HAUS3 data types