Across TCGA cell cohorts, HAUS3 mutation is significantly associated with the RNA expression of many other genes, with 19 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HAUS3-associated genes across cancer lineages are KLK9, H2BC3, and BTN1A1. Each is linked with HAUS3 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAUS3-to-partner and partner-to-HAUS3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAUS3→partner) and Y-score (partner→HAUS3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	KLK9 →	+0.132	+3.878	.003	.003	3	1
LARGE_INTESTINE	H2BC3 →	+0.203	+3.196	<.001	.007	3	1
SKIN	BTN1A1 →	+0.205	+4.095	<.001	.009	3	1
SKIN	DEFB125 →	+0.025	+4.415	.001	.007	3	1
SKIN	ADIPOQ →	+0.007	+5.217	<.001	<.001	3	1
SKIN	PRAMEF17 →	+0.012	+5.022	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 19 associations by consensus.

Exploration

HAUS3 survival (RNA) · tumor vs normal (RNA) · all HAUS3 data types