HAUS1

Across TCGA pan-cancer cohorts, HAUS1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated HAUS1 data layer compared with 27 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher HAUS1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated HAUS1 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

COAD, HNSC, and LUAD are the cancer types where HAUS1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Quartile	III,IV	0.836	1.000	.030	30	view →
HNSC	OS	Median	All	0.607	0.824	.004	27	view →
LUAD	DFS	Quartile	II,III,IV	0.971	0.580	.005	20	view →
LSCC	OS	Quartile	All	0.966	0.648	.003	18	view →
OV	DFS	Median	All	0.855	1.000	.026	4	view →
CCRCC	DFS	Quartile	All	0.951	0.604	.009	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

HAUS1–COAD (DFS)

Open the COAD breakdown →