HAUS1

Across TCGA pan-cancer cohorts, HAUS1 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of HAUS1’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where HAUS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HAUS1 is over-expressed in tumor, although a few such as KICH and PRAD show the opposite, repressed pattern.

HNSC, KIRC, and LIHC are the cancer types where HAUS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HAUS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.877	<.001	12	view →
KIRC	All	IV	+0.642	<.001	12	view →
LIHC	Male	II,III,IV	+1.258	<.001	9	view →
BLCA	All	All	+0.675	<.001	8	view →
KIRP	All	II,III,IV	+0.574	.004	7	view →
STAD	All	II,III,IV	+0.631	<.001	6	view →
BRCA	All	II,III,IV	+0.573	<.001	6	view →
LUSC	All	All	+0.738	<.001	5	view →
COAD	Male	All	+0.456	.007	4	view →
CHOL	Female	All	+1.866	<.001	3	view →
READ	All	II,III,IV	+0.577	.002	3	view →
LUAD	All	All	+0.339	<.001	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

HAUS1–HNSC

Open the HNSC breakdown →