HAT1

Across TCGA patient cohorts, HAT1 protein abundance is significantly associated with the RNA expression of many other genes, with 15,528 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HAT1-associated genes across cancer lineages are GINS1, CENPI, and OIP5. Each is linked with HAT1 in more than 9 cancer types. Because this analysis shows association rather than direction, both HAT1-to-partner and partner-to-HAT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAT1 versus GINS1 in UCEC, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAT1→partner) and Y-score (partner→HAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GINS1 →	+1.206	+0.463	<.001	<.001	3	10
UCEC	CENPI →	+0.987	+0.398	<.001	<.001	3	10
LSCC	OIP5 →	+0.823	+0.585	<.001	<.001	3	10
LUAD	MCM4 →	+0.877	+0.427	<.001	<.001	3	10
UCEC	ASF1B →	+1.185	+0.402	<.001	<.001	3	10
BRCA	EZH2 →	+1.073	+0.526	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,528 associations by consensus.

HAT1 vs GINS1 — UCEC

Explore this scatter interactively →