HAT1

Across TCGA cell cohorts, HAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,622 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible HAT1-associated GO terms across cancer lineages are Regulation of mitotic nuclear division, Mitotic spindle assembly checkpoint signaling, and Spindle assembly checkpoint signaling. Each is linked with HAT1 in more than 18 cancer types. Because this analysis shows association rather than direction, both HAT1-to-partner and partner-to-HAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic nuclear division grouped by HAT1-low versus HAT1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAT1→partner) and Y-score (partner→HAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Regulation of mitotic nuclear division →	+0.137	+1.608	<.001	<.001	3	19
KIDNEY	Mitotic spindle assembly checkpoint signaling →	+0.191	+0.862	<.001	<.001	3	19
KIDNEY	Spindle assembly checkpoint signaling →	+0.191	+0.862	<.001	<.001	3	19
KIDNEY	Mitotic spindle checkpoint signaling →	+0.191	+0.862	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	Regulation of G2/M transition of mitotic cell cycle →	+0.074	+0.971	<.001	<.001	3	19
BREAST	Positive regulation of mitotic cell cycle phase transition →	+0.104	+0.910	<.001	.002	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,622 associations by consensus.

Regulation of mitotic nuclear division by HAT1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →