HASPIN

Across TCGA patient cohorts, HASPIN RNA expression is significantly associated with the protein abundance of many other proteins, with 23,415 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HASPIN-associated proteins across cancer lineages are RRM2, HAT1, and MCM2. Each is linked with HASPIN in more than 9 cancer types. Because this analysis shows association rather than direction, both HASPIN-to-partner and partner-to-HASPIN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HASPIN versus RRM2 in UCEC, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HASPIN→partner) and Y-score (partner→HASPIN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RRM2 →	+0.951	+1.062	<.001	<.001	3	10
LSCC	HAT1 →	+0.537	+0.919	<.001	<.001	3	10
UCEC	MCM2 →	+0.861	+1.116	<.001	<.001	3	10
GBM	SMC2 →	+0.873	+0.923	<.001	<.001	3	10
GBM	SMC4 →	+0.825	+0.908	<.001	<.001	3	10
LUAD	BUB1B_S543 →	+0.844	+0.841	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,415 associations by consensus.

HASPIN vs RRM2 — UCEC

Explore this scatter interactively →