HAS2

Across TCGA cell cohorts, HAS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,646 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HAS2-associated GO terms across cancer lineages are Positive regulation of epithelial to mesenchymal transition, Collagen metabolic process, and Endodermal cell differentiation. Each is linked with HAS2 in more than 9 cancer types. Because this analysis shows association rather than direction, both HAS2-to-partner and partner-to-HAS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of epithelial to mesenchymal transition grouped by HAS2-low versus HAS2-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAS2→partner) and Y-score (partner→HAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of epithelial to mesenchymal transition →	+0.175	+2.240	<.001	.001	3	10
BONE	Collagen metabolic process →	+0.274	+2.224	<.001	<.001	3	9
BONE	Endodermal cell differentiation →	+0.201	+2.702	<.001	<.001	3	9
BONE	Positive regulation of T cell tolerance induction →	+1.487	+3.498	<.001	<.001	3	8
BONE	Collagen fibril organization →	+0.386	+2.226	<.001	<.001	3	8
BONE	Positive regulation of actin filament bundle assembly →	+0.188	+2.222	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,646 associations by consensus.

Positive regulation of epithelial to mesenchymal transition by HAS2 expression — BONE

Explore this box plot interactively →