Across TCGA patient cohorts, HAPLN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,376 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HAPLN4-associated GO terms across cancer lineages are Nucleobase-containing compound transport, Cytoskeleton-dependent intracellular transport, and Obsolete regulation of histone H3-K4 methylation. Each is linked with HAPLN4 in more than 12 cancer types. Because this analysis shows association rather than direction, both HAPLN4-to-partner and partner-to-HAPLN4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAPLN4→partner) and Y-score (partner→HAPLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Nucleobase-containing compound transport →	+0.063	+0.042	<.001	.002	3	12
SCLC	Cytoskeleton-dependent intracellular transport →	+0.073	+1.196	<.001	<.001	3	12
SCLC	Obsolete regulation of histone H3-K4 methylation →	+0.164	+1.057	.001	<.001	2	12
ESCA	Maintenance of cell number →	+0.066	+0.046	<.001	<.001	3	11
STAD	Negative regulation of cell projection organization →	+0.043	+0.016	<.001	<.001	2	12
ESCA	Peptidyl-threonine modification →	+0.060	+0.034	<.001	.002	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,376 associations by consensus.

Exploration

HAPLN4 survival (RNA) · tumor vs normal (RNA) · all HAPLN4 data types