Across TCGA cell cohorts, HAPLN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,739 significant associations in total. BONE shows the largest number of these associations.

The most reproducible HAPLN4-associated GO terms across cancer lineages are Regulation of double-strand break repair, Positive regulation of DNA metabolic process, and Positive regulation of DNA recombination. Each is linked with HAPLN4 in more than 6 cancer types. Because this analysis shows association rather than direction, both HAPLN4-to-partner and partner-to-HAPLN4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HAPLN4→partner) and Y-score (partner→HAPLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of double-strand break repair →	+0.078	+0.761	<.001	.002	3	7
BONE	Positive regulation of DNA metabolic process →	+0.074	+0.670	.001	.002	3	7
BONE	Positive regulation of DNA recombination →	+0.108	+0.603	<.001	<.001	3	6
BONE	DNA conformation change →	+0.134	+0.524	.001	.007	3	6
LUNG_NSCLC_LUAD	Microtubule cytoskeleton organization involved in mitosis →	+0.044	+0.049	.003	.007	2	7
LUNG_NSCLC_LUAD	Heterochromatin organization →	+0.031	+0.064	.002	.005	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,739 associations by consensus.

Exploration

HAPLN4 survival (RNA) · tumor vs normal (RNA) · all HAPLN4 data types