Across TCGA cell cohorts, HAPLN4 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HAPLN4-associated genes across cancer lineages are FABP12, LCE6A, and C20orf85. Each is linked with HAPLN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAPLN4-to-partner and partner-to-HAPLN4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAPLN4→partner) and Y-score (partner→HAPLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	FABP12 →	+0.116	+4.981	.002	.008	3	1
CNS	LCE6A →	+0.038	+5.754	<.001	.002	3	1
BLOOD_Leukemia	C20orf85 →	+0.036	+4.969	<.001	.003	3	1
BLOOD_Leukemia	IL22 →	+0.037	+5.569	<.001	.001	3	1
BLOOD_Leukemia	LRRTM3 →	+0.004	+4.539	<.001	.007	3	1
BLOOD_Leukemia	PRAMEF7 →	+0.009	+4.539	.008	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

Exploration

HAPLN4 survival (RNA) · tumor vs normal (RNA) · all HAPLN4 data types