HAPLN2

Across TCGA patient cohorts, HAPLN2 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,521 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HAPLN2-associated proteins across cancer lineages are ZSCAN18, GFPT2, and BRMS1L. Each is linked with HAPLN2 in more than 3 cancer types. Because this analysis shows association rather than direction, both HAPLN2-to-partner and partner-to-HAPLN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAPLN2 versus ZSCAN18 in HNSC, with a Pearson correlation of 0.25.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAPLN2→partner) and Y-score (partner→HAPLN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ZSCAN18 →	+0.566	+0.460	<.001	.008	3	4
CCRCC	GFPT2 →	-1.036	-0.428	<.001	.008	3	4
OV	BRMS1L →	+0.309	+0.247	.002	.003	3	4
LSCC	SPCS3 →	-0.568	-0.203	<.001	.008	3	4
GBM	RPL7 →	-0.566	-1.828	<.001	<.001	3	4
GBM	STXBP1 →	+0.871	+1.954	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,521 associations by consensus.

HAPLN2 vs ZSCAN18 — HNSC

Explore this scatter interactively →