HAO2

Across TCGA patient cohorts, HAO2 protein abundance is significantly associated with the protein abundance of many other proteins, with 5,237 significant associations in total. CCRCC shows the largest number of these associations.

The most reproducible HAO2-associated proteins across cancer lineages are EIF2AK2, ZNF507_S404, and IFIT3. Each is linked with HAO2 in more than 1 cancer types. Because this analysis shows association rather than direction, both HAO2-to-partner and partner-to-HAO2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAO2 versus EIF2AK2 in BRCA, with a Pearson correlation of -0.54.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAO2→partner) and Y-score (partner→HAO2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	EIF2AK2 →	-0.859	-1.161	<.001	.002	3	2
BRCA	ZNF507_S404 →	-1.446	-0.953	<.001	<.001	3	1
BRCA	IFIT3 →	-1.223	-1.059	.002	.001	3	1
BRCA	ISG15 →	-1.645	-1.013	<.001	.001	3	1
BRCA	MX1 →	-1.431	-1.046	.001	<.001	3	1
BRCA	ANKLE2_S914 →	-1.303	-0.953	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,237 associations by consensus.

HAO2 vs EIF2AK2 — BRCA

Explore this scatter interactively →