HAL

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HAL RNA expression is significantly associated with the protein abundance of many other proteins, with 11,928 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HAL-associated proteins across cancer lineages are S100A12, AZU1, and RETN. Each is linked with HAL in more than 5 cancer types. Because this analysis shows association rather than direction, both HAL-to-partner and partner-to-HAL results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAL versus S100A12 in GBM, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAL→partner) and Y-score (partner→HAL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMS100A12 →+1.724+0.480<.001<.00136
GBMAZU1 →+1.069+0.364<.001<.00136
GBMRETN →+1.252+0.310<.001<.00135
LUADS100P →+1.938+1.417<.001<.00135
GBMARG1 →+1.036+0.451<.001<.00135
GBMCAMP →+1.639+0.280<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,928 associations by consensus.

HAL vs S100A12 — GBM

Per-sample scatter of HAL vs S100A12 in GBM (Pearson r = 0.65).

Explore this scatter interactively →

Exploration