HADHBP1

Across TCGA pan-cancer cohorts, HADHBP1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of HADHBP1’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where HADHBP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types HADHBP1 is over-expressed in tumor, although a few such as KIRC and PAAD show the opposite, repressed pattern.

COAD, KIRC, and PAAD are the cancer types where HADHBP1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in HADHBP1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	II,III,IV	+0.173	.003	4	view →
KIRC	Male	II,III,IV	−0.046	.004	4	view →
PAAD	All	All	−0.050	.036	2	view →
THCA	Male	II,III,IV	−0.048	.038	1	view →
CHOL	All	All	+0.031	.038	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

HADHBP1–COAD

Open the COAD breakdown →