HADHB

Across TCGA patient cohorts, HADHB protein abundance is significantly associated with the RNA expression of many other genes, with 11,984 significant associations in total. COAD shows the largest number of these associations.

The most reproducible HADHB-associated genes across cancer lineages are HMGXB4, LOX, and SPRED1. Each is linked with HADHB in more than 4 cancer types. Because this analysis shows association rather than direction, both HADHB-to-partner and partner-to-HADHB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HADHB versus HMGXB4 in OV, with a Pearson correlation of -0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HADHB→partner) and Y-score (partner→HADHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	HMGXB4 →	-0.503	-0.364	<.001	<.001	3	5
OV	LOX →	-1.589	-0.312	<.001	.001	3	4
OV	SPRED1 →	-0.568	-0.283	.003	.006	3	4
OV	ZNF530 →	-0.739	-0.304	<.001	<.001	3	4
LUAD	RPL7AP10 →	-0.657	-0.210	<.001	<.001	3	4
OV	SLC4A7 →	-0.622	-0.304	.002	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,984 associations by consensus.

HADHB vs HMGXB4 — OV

Explore this scatter interactively →