HACL1

Across TCGA cell cohorts, HACL1 protein abundance is significantly associated with the RNA expression of many other genes, with 2,874 significant associations in total. BLOOD_Myeloma shows the largest number of these associations.

The most reproducible HACL1-associated genes across cancer lineages are H6PD, APOBEC3F, and TAS2R10. Each is linked with HACL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both HACL1-to-partner and partner-to-HACL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HACL1 versus H6PD in STOMACH, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HACL1→partner) and Y-score (partner→HACL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	H6PD →	+1.705	+1.908	.006	.001	2	6
SOFT_TISSUE	APOBEC3F →	+2.067	+0.911	.002	.001	3	5
BLOOD_Myeloma	TAS2R10 →	-0.399	-1.157	.002	.007	3	4
URINARY_TRACT	SCAMP2 →	+0.900	+1.097	.003	.005	3	4
PANCREAS	TMED3 →	+1.115	+1.533	<.001	.003	3	4
STOMACH	SEC31A →	+1.517	+1.432	.004	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,874 associations by consensus.

HACL1 vs H6PD — STOMACH

Explore this scatter interactively →