HACE1

Across TCGA patient cohorts, HACE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,854 significant associations in total. GBM shows the largest number of these associations.

The most reproducible HACE1-associated proteins across cancer lineages are SQOR, PREP, and ARID1B. Each is linked with HACE1 in more than 5 cancer types. Because this analysis shows association rather than direction, both HACE1-to-partner and partner-to-HACE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HACE1 versus SQOR in GBM, with a Pearson correlation of -0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HACE1→partner) and Y-score (partner→HACE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SQOR →	-0.693	-0.632	<.001	<.001	3	6
OV	PREP →	+0.300	+0.793	<.001	<.001	3	6
LSCC	ARID1B →	+0.255	+0.598	<.001	<.001	3	6
GBM	COPG1 →	-0.237	-0.429	<.001	<.001	3	5
GBM	EPS8L2 →	-0.524	-0.314	<.001	.006	3	5
HNSC	PSME2 →	-0.512	-0.563	<.001	.005	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,854 associations by consensus.

HACE1 vs SQOR — GBM

Explore this scatter interactively →