HACD1

Across TCGA patient cohorts, HACD1 protein abundance is significantly associated with the RNA expression of many other genes, with 1,243 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HACD1-associated genes across cancer lineages are ANKRD1, ESPN, and LRRTM3. Each is linked with HACD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HACD1-to-partner and partner-to-HACD1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HACD1 versus ANKRD1 in HNSC, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HACD1→partner) and Y-score (partner→HACD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	ANKRD1 →	+2.455	+0.780	<.001	<.001	3	2
HNSC	ESPN →	-0.942	-0.733	<.001	.003	3	2
HNSC	LRRTM3 →	+0.566	+0.988	<.001	<.001	3	2
LUAD	PCP4L1 →	-2.768	-0.763	.004	.002	3	2
HNSC	BMP7 →	-1.195	-0.722	.003	.001	3	1
HNSC	SLC52A3 →	-0.602	-0.542	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,243 associations by consensus.

HACD1 vs ANKRD1 — HNSC

Explore this scatter interactively →