HACD1

Across TCGA patient cohorts, HACD1 mutation is significantly associated with the RNA expression of many other genes, with 503 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HACD1-associated genes across cancer lineages are MIR5787, EIF2S2P7, and RNU5F-4P. Each is linked with HACD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both HACD1-to-partner and partner-to-HACD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR5787 grouped by HACD1-low versus HACD1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HACD1→partner) and Y-score (partner→HACD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR5787 →	+0.298	+4.412	<.001	.006	3	3
BLCA	EIF2S2P7 →	+0.047	+5.685	<.001	.003	3	2
SKCM	RNU5F-4P →	+0.337	+3.838	<.001	.006	3	2
UCEC	RPS17P17 →	+0.146	+2.224	.004	.009	3	2
BLCA	LINC01654 →	+0.028	+5.685	<.001	.003	3	1
BLCA	RN7SL66P →	+0.160	+5.177	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 503 associations by consensus.

MIR5787 by HACD1 expression — LUSC

Explore this box plot interactively →