HACD1

Across TCGA patient cohorts, HACD1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible HACD1-associated genes across cancer lineages are GMP, Adipocytes, and Class-switched memory B-cells. Each is linked with HACD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HACD1-to-partner and partner-to-HACD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by HACD1-low versus HACD1-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HACD1→partner) and Y-score (partner→HACD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	GMP →	+0.032	+2.849	.020	.020	3	1
UCEC	Adipocytes →	+0.027	+2.659	<.001	.001	3	1
UCEC	Class-switched memory B-cells →	-0.052	-2.000	.041	.032	2	1
UCEC	lymphatic Endothelial cells →	-0.021	-2.281	.045	.035	2	1
UCEC	Endothelial cells →	-0.043	-3.764	.011	<.001	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

GMP by HACD1 expression — LUSC

Explore this box plot interactively →