HACD1

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, HACD1 mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible HACD1-associated genes across cancer lineages are ECE2. Each is linked with HACD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both HACD1-to-partner and partner-to-HACD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ECE2 grouped by HACD1-low versus HACD1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HACD1→partner) and Y-score (partner→HACD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEECE2 →+0.381+4.054<.001.00431
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

ECE2 by HACD1 expression — LARGE_INTESTINE

Box plot of ECE2 in HACD1-low vs HACD1-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration