HAAO

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, HAAO RNA expression is significantly associated with the protein abundance of many other proteins, with 13,981 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible HAAO-associated proteins across cancer lineages are RTN1, MVB12B_S224, and DPYSL2. Each is linked with HAAO in more than 4 cancer types. Because this analysis shows association rather than direction, both HAAO-to-partner and partner-to-HAAO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAAO versus RTN1 in OV, with a Pearson correlation of 0.52.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (HAAO→partner) and Y-score (partner→HAAO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVRTN1 →+0.523+0.656<.001<.00135
OVMVB12B_S224 →+0.637+0.699.008.00235
HNSCDPYSL2 →+0.368+0.783<.001<.00135
OVEFEMP2 →+0.734+0.889<.001<.00135
OVELMO1 →+0.393+0.661<.001<.00135
OVABI3 →+0.541+0.710<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 13,981 associations by consensus.

HAAO vs RTN1 — OV

Per-sample scatter of HAAO vs RTN1 in OV (Pearson r = 0.52).

Explore this scatter interactively →

Exploration