HAAO

Across TCGA patient cohorts, HAAO protein abundance is significantly associated with the RNA expression of many other genes, with 19,092 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible HAAO-associated genes across cancer lineages are ENPP2, CLEC1A, and RCAN2. Each is linked with HAAO in more than 8 cancer types. Because this analysis shows association rather than direction, both HAAO-to-partner and partner-to-HAAO results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, HAAO versus ENPP2 in GBM, with a Pearson correlation of 0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (HAAO→partner) and Y-score (partner→HAAO) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ENPP2 →	+1.409	+0.299	<.001	<.001	3	9
BRCA	CLEC1A →	+0.847	+0.652	<.001	<.001	3	9
GBM	RCAN2 →	+1.196	+0.317	<.001	<.001	3	9
BRCA	CASP4LP →	+0.711	+0.480	<.001	<.001	3	9
BRCA	CNRIP1 →	+1.154	+0.632	<.001	<.001	3	8
OV	KLF2 →	+1.109	+0.558	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,092 associations by consensus.

HAAO vs ENPP2 — GBM

Explore this scatter interactively →